McAuley L, Pham B, Tugwell P, Moher D. Does the inclusion of grey literature influence estimates of intervention effectiveness reported in meta-analyses? Methods Guide for Comparative Effectiveness Reviews [Internet]. Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research. 2017;12:e0176210. PubMed Google Scholar. Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials. Cherry-picking by trialists and meta-analysts can drive conclusions about intervention efficacy. However, a reasonable argument could be made that, when the same information is available in both a published peer-reviewed article and an abstract for a given study, including the abstract in a systematic review would be superfluous and/or ill-advised because a likely more comprehensive and dependable source of the information, i.e., the peer-reviewed article, is available. Consistency of phase III clinical trial abstracts presented at an annual meeting of the American Society of Clinical Oncology compared with their subsequent full-text publications. The current review … In our review, it would have been possible to exclude conference abstracts and retain accurate and precise results. The most frequent scenario for publication bias is when studies with “positive” (or “significant”) results are selectively published, or are published sooner, than studies with either null or negative results. Mayo-Wilson E, Li T, Fusco N, Bertizzolo L, Canner JK, Cowley T, Doshi P, Ehmsen J, Gresham G, Guo N, et al. Online ahead of print.ABSTRACT This systematic review examined the interrelationship between concomitant diabetes mellitus (DM) and peripheral arterial disease (PAD). 2003;361:978–9. J Clin Epidemiol. Int J Technol Assess Health Care. https://doi.org/10.1002/14651858.MR000006.pub3. Therapeutic hip arthroscopy investigations that reported on adverse events or complications were included. This is important to ensure that the clinical questions and scope of the project are understood adequately by the external agency group and then adequately addressed in the systematic review. Appl Health Econ Health Policy. J Clin Oncol. Conference calls are recommended prior to t… Publication bias: the case for an international registry of clinical trials. Although these recommendations generally do not espouse including conference abstracts in systematic reviews, they provide excellent guidance on when including abstracts should be considered: • Reviewers should routinely consider conducting a search of conference abstracts and proceedings to identify unpublished or unidentified studies. © 2020 BioMed Central Ltd unless otherwise stated. PLoS One. Therefore, the presence of a journal article might obviate the need for including a corresponding conference abstract in a systematic review, unless unique outcomes are reported in the abstract. Mayo-Wilson E, Fusco N, Li T, Hong H, Canner JK, Dickersin K. Multiple outcomes and analyses in clinical trials create challenges for interpretation and research synthesis. 2007;18(2):MR000011. J Pediatr Surg. https://doi.org/10.1002/14651858.MR000006.pub3, https://www.elsevier.com/solutions/embase-biomedical-research/embase-coverage-and-content, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/, https://doi.org/10.1186/s13643-019-1188-0. We use cookies to help provide and enhance our service and tailor content and ads. 2000;356:1228–31. • Consult the TEP [Technical Expert Panel] for suggestions on particular conferences to search and search those conferences specifically. Hopewell S. Assessing the impact of abstracts from the Thoracic Society of Australia and New Zealand in Cochrane reviews. The PRISMA extension for Abstracts was published in 2013. Am Stat. The PRISMA for Abstracts checklist may help authors provide abstracts that facilitate peer review for pre-publication and conference selection, enable efficient perusal of electronic search results, provide assessment of the validity of a systematic review … J Clin Epidemiol. 2017;91:95–110. Hopewell S, Loudon K, Clarke MJ, Oxman AD, Dickersin K. Publication bias in clinical trials due to statistical significance or direction of trial results. Syst Rev 8, 264 (2019). Weizman AV, Griesman J, Bell CM. Our analysis found that inclusion of reports that were conference abstracts did not change the strength or precision of our meta-analytic results. 1). The most frequent types of conflicting information between abstract and full-length journal article have pertained to authors or authorship order, sample size, and estimates of treatment effects (their magnitude or, less frequently, direction) [25,26,27,28,29,30,31]. In addition, to examine the impact of including the abstracts, a sensitivity analysis should always be completed with and without conference abstracts. Arguments against including conference abstracts are that (1) searching for abstracts is resource-intensive, (2) abstracts may not contain adequate information, and (3) the information in abstracts may not be dependable. The dilemma facing a systematic reviewer is to determine when it might. We and others argue that the failure of trialists to honor their commitment to patients (that patient participation would contribute to science) represents an ethical problem [5, 6]. Based on the available evidence and on our experience, we suggest that instead of arbitrarily deciding to include conference abstracts or not in a systematic review, systematic reviewers should consider the availability of evidence. We screened abstracts of five WCPs held from 2008 to 2016 to find abstracts describing SRs. We also refrain from making specific suggestions for what should be construed as “reasonable precision” because of the various problems inherent in the use of statistical significance (e.g., arbitrariness, dependence on sample size) and the arbitrary thresholds for precision that use of statistical significance can engender [38,39,40,41]. Submit Encore Presentation abstracts as either Original Research, Systematic Review/Meta-Analysis, Case Reports, Advances in International Clinical Pharmacy Practice, Education, or Training, or Clinical Pharmacy Forum and select "encore" when prompted, providing the original citation, and a copy of the original abstract. The median adherence by abstracts to each PRISMA-A checklist item was 33% (interquartile range: 29% to 42%). Correspondence to Both authors read and approved the final manuscript. Instead of arbitrarily deciding to include or exclude conference abstracts in systematic reviews, we suggest that systematic reviewers should consider the availability of evidence informing the review. One aspect to consider is the scope of the review. A literature search is distinguished from, but integral to, a literature review. Nature. The conference abstracts are published to share new knowledge with those unable to attend the conference. Scherer, R.W., Saldanha, I.J. Others who have incorporated conference abstracts for decision-making have noted that the lack of, or conflicting results in, published evidence often requires inclusion of conference abstracts [36]. PRISMA for Abstracts: Reporting Systematic Reviews in Journal and Conference Abstracts… Taken together, the evidence reviewed in this paper (summarized in Table 1) suggests that systematic reviewers should take a more nuanced approach to inclusion of conference abstracts. Evidence shows that research abstracts are commonly inconsistent with their corresponding full reports, and may mislead readers. Evidence from a recent systematic review indicates that the inclusion of gray literature (defined more broadly than just conference abstracts) in meta-analyses may change the results from significant to non-significant or from non-significant to significant, or may not change the results [24, 33]. Scherer RW, Meerpohl JJ, Pfeifer N, Schmucker C, Schwarzer G, von Elm E. Full publication of results initially presented in abstracts. A systematic, reproducible and transparent methodological approach is a key component in systematic reviews. Worldviews Evid-Based Nurs. Scientists rise up against statistical significance. von Elm E, Costanza MC, Walder B, Tramer MR. More insight into the fate of biomedical meeting abstracts: a systematic review. While meta-epidemiologic studies have shown that inclusion of abstracts does not greatly impact meta-analytic results, it can sometimes make a difference. Publication bias in clinical research. Resources for conducting a systematic review research. BMJ. Our objectives in this commentary are to summarize the existing evidence both for and against the inclusion of conference abstracts in systematic reviews and provide suggestions for systematic reviewers when deciding whether and how to include conference abstracts in systematic reviews. Compared with abstracts included in publications, conference abstracts more often identified themselves in the title as a systematic review, meta-analysis, or both (87% vs. 75%; P = 0.015) … A view from the trenches. • We do not recommend using conference abstracts for assessing selective outcome reporting and selective analysis reporting, given the variable evidence of concordance between conference abstracts and their subsequent full-text publications [1]. A simple yes or no to the question “Should we include conference abstracts in our systematic review?” is neither sufficient nor appropriate. Center for Clinical Trials and Evidence Synthesis, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Room E6138, Baltimore, MD, 21205, USA, Center for Evidence Synthesis in Health, Department of Health Services, Policy, and Practice (Primary), Brown University School of Public Health, Providence, RI, USA, Department of Epidemiology (Joint), Brown University School of Public Health, Providence, RI, USA, You can also search for this author in J Clin Epidemiol. Benzies KM, Premji S, Hayden KA, Serrett K. State-of-the-evidence reviews: advantages and challenges of including grey literature. EMBASE content: List of conferences covered in Embase. Terms and Conditions, From a systematic reviewer’s perspective, even if the unpublished abstracts were a random 3 in 10 abstracts, restricting a systematic review search to only the published literature would amount to the loss of an immense amount of information and a corresponding loss of precision in meta-analytic estimates of treatment effect. 2019;73:20–5. Cochrane Database of Syst Rev. Current guidelines are conflicting. Under given circumstances, it is worthwhile to search for and include results from conference abstracts in systematic reviews. Abstract: A Systematic Review of Career Counseling Interventions for Survivors of IPV (Society for Social Work and Research 22nd Annual Conference - Achieving Equal Opportunity, Equity, and Justice) … 1987;22:11–3. IJS developed Fig. However, EMBASE, a commonly searched database during systematic reviews, now includes conference abstracts from important medical conferences, dating back to 2009 [17]. Conference Abstracts; Topics; ... A systematic review of the literature was conducted to understand the salutary benefits of yoga for clients who are at risk for falls because of … While identifying and cataloging unpublished studies from conference proceedings is generally recognized as a good practice during systematic reviews, controversy remains whether to include study results that are reported in conference abstracts. For example, will the conference abstracts be used to inform policy based on a cadre of systematic reviews or only used within a single review? Once you have an initial idea, search for already published literature on the topic. The 12-item checklist gives authors a framework for condensing their systematic review into the essentials for a journal of conference … Data sharing: Raw data collected during this study are available on Open Science Framework; link: https://osf.io/hpced/. Manage cookies/Do not sell my data we use in the preference centre. From conference abstract to full paper: differences between data presented in conferences and journals. Of conference abstracts in systematic reviews: //osf.io/hpced/ committees or included in trial registries: the National Press... Sk, Falagas ME is not a matter of random chance Comparative Effectiveness reviews [ Internet.. 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